Is affordable tirzepatide gone for good?
As of March 26, 2025, the U.S. Food and Drug Administration (FDA) has officially declared that the shortage of tirzepatide —found in brand-name medications like Mounjaro and Zepbound — over. As a result, compounding pharmacies are no longer allowed to produce compounded versions of tirzepatide. However, whatever the pharmacy has in stock they can keep selling past March 19th until that supply runs out. Here’s what this means for you.
Why compounded tirzepatide was allowed
During the nationwide shortage, the FDA temporarily allowed compounding pharmacies to create their own versions of tirzepatide to meet urgent patient needs. This was never a permanent solution, but rather a stopgap measure to ensure continued access to a vital medication during limited supply.
Key discontinuation dates
February 18, 2025: Deadline for 503A facilities (state-licensed pharmacies and physicians) to stop compounding tirzepatide.
March 19, 2025: Deadline for 503B outsourcing facilities to cease production.
What this means for you
If you’ve been using compounded tirzepatide, here’s what you need to know moving forward:
1. Transition to FDA-approved medications
Speak with your healthcare provider about transitioning to FDA-approved tirzepatide options such as Mounjaro or Zepbound. These medications are now more widely available following the resolution of the shortage.
2. Consider financial assistance programs
The high cost of brand-name medications can be a concern. Thankfully, companies like Eli Lilly offer savings programs and direct-to-consumer platforms to help make Zepbound more affordable. Our clinic can guide you in exploring these options.
3. Explore alternative treatment options
There may be other medications available, such as different GLP-1 receptor agonists or FDA-approved weight loss treatments that might suit your medical needs and financial situation better. Your provider can walk you through what’s best for your health journey.
4. Maintain open communication with your healthcare team
Regular follow-ups and honest conversations with your provider are key to staying on track. We’ll help you adjust your treatment plan as needed, support lifestyle changes, and ensure continuity of care.
Important health & safety considerations
Avoid unverified sources
It’s extremely important to avoid seeking compounded tirzepatide from unauthorized or unregulated sources. Medications from these outlets may be unsafe, ineffective or even harmful.
Stay informed
Regulations and availability of medications can change rapidly. Make sure you're keeping up with accurate, reliable information and staying in touch with your healthcare team.
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